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history focus27eueuMicroscopyandAnalysis | July/August 2017As part of the 75th anniversary celebration, the MSA have invited all living past presidents of MSA to join them and the majority will be in attendance. M&M 2017 will provide a unique opportunity for today's members to meet and celebrate past Society leaders whose efforts have made MSA the international leader in microscopy and microanalysis that it is today. MSA will also be marking its 75th anniversary with displays and slide shows of historical photos from different eras in the Society's history. Prominently featured will be the photo above, which depicts leaders in the new field of electron microscopy at the inaugural meeting in Chicago in 1942. Attendees will have the opportunity to pose for selfies with this photo as a backdrop.correction development, founding CEOS, which delivered the first commercial aberration-corrected TEM in the late 1990s. Early work was also carried out in the US by the group of Albert Crewe, followed by the work of Ondrej Krivanek's group, which also led to commercialization in the late 1990's, by his company, Nion."The first "high-resolution" electron microscopes had a resolution of around ten nanometres, or 100 Angströms, and by 1964, resolution improved to 4 Å," says Marko. "But we didn't reach sub-angström resolution until aberration correction was developed, which constituted a revolution in resolution". At the same time, the rise of super-resolution light microscopy was underway. Given this and the increasing diversity of microscopy and microanalysis techniques published and presented at Society meetings, come 1991, the organisation changed its name from the Electron Microscopy Society of America to the Microscopy Society of America.An eye on the futureIn recent years, MSA has continued to flourish, and right now, Marko is excited that the current President, Ian Anderson, has put top priority on welcoming more and more young researchers into leadership roles in the Society. Anderson has established a Student Council, and this year, for the first time, students are organising a pre-meeting congress.The MSA Archivist is also avidly watching what he describes as a convergence in resolution between materials science and biology. Largely thanks to the development of direct-electron detectors and sophisticated image-processing software, cryo-electron microscopy can be used to create near-atomic-resolution models of biological macromolecules.Crucially, these macromolecules models are comparable to structures determined by X-ray crystallography, but are obtained without the need for crystallization. These breakthroughs were underpinned by the pioneering work of Nobelist Aaron Klug and successors D.Caspar, D. DeRosier, J. the microscopeFrank, and many others."Even with dose-sensitive biological specimens, we're now getting very close to atomic resolution, and this is a major driver in the field of biology," says Marko. "We are a technology-based society, so researchers can come to our meetings to learn about this and other up-and-coming technologies relevant to their applications." "I always encourage researchers to come to the Meeting to learn about technology that is outside their application," he adds. "If they do this, they can learn how other researchers do things and how this might help themselves."left First series-produced commercial TEM, from Siemens Siemensbelow Founding meeting, 1942, Sherman Hotel, Chicago. Left to right: G. L. Clark (Meeting Chairman), James Hillier, O.S. Duffendack, L. A. Matheson, V. K. Zworykin

news28eueuJuly/August 2017 | MicroscopyandAnalysisFirst microsphere nanoscope launchedFrom nearly 60 submis-sions to its 2017 Paper Award, WITec has selected what it believes are the three best publications.Winning papers were written by researchers from Ireland, Portugal and Germany who had used WITec correlative confocal Raman microscopes to study transition metal dichalcogenides, textile fibers and cement.According to the company's jury, these papers show in remarkable detail how information on the chemical and structural composition of a material, obtained through this non-destructive technique, can lead to a more comprehensive understanding of a wide range of materials.Maria O'Brien from Trinity College in Dublin, Ireland, received the Gold Paper Award for her publication on mapping low-frequency Raman modes of four transition metal dichalcogenides (TMDCs): MoS2, MoSe2, WS2 and WSe2, as published in Scientific Reports.Together with Niall McEvoy, Damien Hanlon, Toby Hallam, Jonathan Coleman and Georg Duesberg, she used the Raman modes for in-plane and out-of-plane vibrations whose intensities depend on the thickness and the stacking order of the molecules' layers.Meanwhile, Helena Nogueira from the University of Aveiro, Portugal, won the Silver Paper Award for research published in Journal of Raman Spectroscopy. She and co-authors, Sara Fateixa, Manon Wilhelm and Tito Trindade, used three-dimensional Raman imaging and surface enhanced Raman scattering (SERS) to monitor the dyeing process of linen textile fibers with methylene blue.The Bronze Paper Award went to Jonas Higl from the University of Ulm, Germany, for a Raman study on hydrating of cementitious materials. Publishing in Cement and Concrete Research, with colleagues Marcus Köhler and Mika Lindén, he used confocal Raman microscopy to document which structures and molecules are formed during the complex process of hydrating C3S clinker.The annual awards recognize outstanding scientific work published the preceding year that employed a WITec device as part of its experimental setup.Evaluation criteria include the significance of the results for the scientific community and the originality of the techniques used.UK-based nanotechnology start-up, LIG Nanowise, has launched Nanopsis, de-scribed as the first widefield optical super resolution microscope that includes the most powerful objective lens in the world.The microsphere nanoscope contains SMAL, a super-resolution, microsphere, amplified lens, with a negative refractive index, pioneered by Professor Lin Li, Director of the Laser Processing Research Centre at the University of Manchester, and Chairman of LIG Nanowise.With a magnification of x400, the objective lens can be attached to standard white light microscopes to dramatically increase resolution, and generate super-resolution virtual images." Researchers can use our microscopes to validate samples and carry out routine work in their own laboratory without having to waste valuable time booking into an imaging centre. This is because unlike other super-resolution technologies, which require a huge amount of expertise, our Nanopsis nanoscopes can be used by anyone with basic undergraduate scientific training," Lin says.The Nanopsis imaging system works by using the microsphere to collect sub-wavelength light and convert it into a virtual super-resolution image.Custom software then stitches these images together, in real-time, to generate full colour, widefield scans of materials and life samples, resolving detail down to 70 nm. Acccording to Lin and colleagues, the super-resolution system rivals STED and STORM for biological imaging and SEM for material imaging – and costs x5 times less than the former, and 10x less than the latter." These reliable, repeatable imaging results are delivered at the frontline of research, rather than part of a disjointed process in an inaccessible centre," highlights Lin. " Our aim is to make super-resolution imaging more accessible to researchers across the globe."Lin and colleagues reckon the imaging system will accelerate research and development in a number of fields including drug discovery, cancer research and microelectronics production.WITec recognises outstanding Raman analysisLeft Gold winners, Maria O'Brien and Niall McEvoy with their workhorse, a WITec confocal Raman microscope.Below left Silver award winners: Helena Nogueira, right, with Sara Feitaxa, centre and Tito Trindade.Below Jonas Higl, centre, receives the 2017 Bronze Paper Award certificate from WITec marketing director Harald Fischer, left with Mika Lindén, right